Since recreational drugs are not legal in the United States, we are not in a position to advise regarding their interactions with Qualia. That said, many people in the biohacking and neurohacking forums have explored many different chemical combinations of various nootropics with cannabis, entheogens, etc. Feel free to go to forums that discuss this topic and learn from other people's experiences, and you can then develop a more informed opinion.
While we obviously can't say anything about use of scheduled narcotics, for safety sake we would encourage at least a 24 hour pause before and after other strong psychoactive chemistry and Qualia.
This review, by a member of the Neurohacker community regarding their personal experience around this topic, may also be of interest and insight: